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Metabolic pathways, genetics, and nutrition
Rate limiting: Glycolysis = PFK-1. TCA = Isocitrate Dehydrogenase.
B1 = Beriberi. B3 = Pellagra (3 Ds). B12 = Pernicious anemia.
LDL carries cholesterol to tissues. HDL carries back to liver.
Southern blot = DNA. Northern = RNA. Western = Protein (SNW DRP).
PKU = Phenylalanine hydroxylase deficiency. Maple syrup = branched chain.
Competitive inhibitor: increased Km, same Vmax. Non-competitive: same Km, decreased Vmax.
ALA synthase = rate limiting. Acute intermittent porphyria = abdominal pain + neuro.
Lesch-Nyhan = HGPRT deficiency. Gout = uric acid crystals.
Von Gierke = G6Pase deficiency. HMP shunt = NADPH + Ribose-5-P.
Iron: Ferritin = storage, Transferrin = transport. Wilson disease = copper.