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Physiology Revision Notes

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Quick Reference — All Topics

1. Cardiac Cycle & Wiggers Diagram

💡 Isovolumetric contraction = Highest O2 consumption. a wave = atrial contraction.

2. Renal Clearance & GFR

💡 Inulin = GFR. PAH = Renal Plasma Flow.

3. Action Potential (Nerve & Cardiac)

💡 Phase 0 (Heart) = Na+ influx. Phase 2 = Ca2+ plateau.

4. Endocrine Hormones (Thyroid, Adrenal)

💡 Cortisol = highest in morning. PTH increases Ca2+, lowers PO4.

5. Respiratory Physiology & Gas Exchange

💡 V/Q ratio = 0.8 normal. Dead space = high V/Q. Shunt = low V/Q.

6. GI Motility & Secretions

💡 Gastrin from G cells. CCK from I cells (contracts gallbladder). Secretin from S cells.

7. Skeletal & Smooth Muscle Physiology

💡 Skeletal: T-tubule→Ryanodine→Ca2+. Smooth: IP3→Ca2+. Rigor = no ATP.

8. Blood Groups & Hemostasis

💡 Intrinsic pathway = PTT. Extrinsic = PT. Common = both. vWF bridges platelets.

9. CNS: Sleep, EEG & Reflexes

💡 REM = desynchronized EEG, dreams, atonia. Delta waves = slow wave sleep.

10. Vision, Hearing & Vestibular

💡 Rods = scotopic (dim light). Cones = photopic (color). Organ of Corti = hearing.